Neurofilaments are flexible polymers that often fold and unfold, but they move in a fully extended configuration
نویسندگان
چکیده
منابع مشابه
To fold, first unfold
The double-ringed GroEL chaperone complex is well-known for capturing partially folded proteins and confi ning them within its central cavity to facilitate folding. GroEL is especially important to proteins that have a complex folding pattern, such as Rubisco. A prominent model of GroEL function suggests that the chaperone fi rst partially unfolds its substrate, disrupting misfolded and inhibit...
متن کاملConstructively Characterizing Fold and Unfold
In this paper we formally state and prove theorems characterizing when a function can be constructively reformulated using the recursion operators fold and unfold, i.e. given a function h, when can a function g be constructed such that h = fold g or h = unfold g? These results are refinements of the classical characterization of fold and unfold given by Gibbons, Hutton and Altenkirch in [6]. Th...
متن کاملBinding-time Improvement and Fold/Unfold Transformation
Binding-time improvement (BTI) is an important preliminary stage in partial evaluation. Some BTI rules can be automated, but the state of the art is that many improvements are still made \by hand" using an ordinary text editor. Mechanically assisted fold/unfold transformation could provide a more systematic framework for BTI.
متن کاملFlexible Continuations in Logic Programs via Unfold/Fold Transformations and Goal Generalization
We consider the use of continuations for deriving e cient logic programs. It is known that both in the case of functional and logic programming, the introduction of continuations is a valuable technique for transforming old programs into new, more e cient ones. However, in general, in order to derive programs with high levels of e ciency, one should introduce continuations according to suitable...
متن کاملMedically unexplained symptoms: how often and why are they missed?
We assessed risk factors affecting the provisional diagnosis of medically unexplained symptoms made by physicians in new patients, in 526 clinical encounters. Comparisons were made between the doctor's initial assessments regarding the nature of symptoms, and the final diagnosis. Physicians were more likely to err on the side of diagnosing the symptoms as medically explained rather than unexpla...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cytoskeleton
سال: 2012
ISSN: 1949-3584
DOI: 10.1002/cm.21039